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Is It Safe to Take Ibuprofen During Pregnancy?

21 Feb 2025
Is It Safe to Take Ibuprofen During Pregnancy

Ibuprofen and Pregnancy: What You Need to Know

If you’re pregnant and dealing with headaches, muscle pain, or fever, you might wonder if ibuprofen (Advil, Motrin) is safe to take. The short answer: Ibuprofen is NOT recommended during pregnancy, especially in the third trimester. While occasional use in early pregnancy may not be harmful, studies suggest that ibuprofen can cause serious risks to the baby, particularly later in pregnancy. Let’s break down the risks, safer alternatives, and when to talk to your doctor.

Why Is Ibuprofen Unsafe During Pregnancy?

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID), which works by reducing inflammation and pain. However, during pregnancy, it can interfere with fetal development and blood flow. Here’s why ibuprofen is considered unsafe, especially in the later stages of pregnancy:

First Trimester Risks (Weeks 1–13)

Possible risk of miscarriage – Some studies suggest ibuprofen may slightly increase the risk of early pregnancy loss.

Second Trimester Risks (Weeks 14–27)

Potential developmental issues – While ibuprofen is less risky in the second trimester, it should still be avoided unless prescribed by a doctor.

Third Trimester Risks (Weeks 28–40)

Premature closure of the ductus arteriosus – This vital blood vessel helps your baby’s heart and lungs develop. Taking ibuprofen can cause it to close too early, leading to heart and lung problems.
Low amniotic fluid (oligohydramnios) – Ibuprofen can reduce amniotic fluid levels, which is essential for baby’s movement and lung development.
Delayed labor – NSAIDs may interfere with the body’s natural labor process, increasing the risk of complications. Because of these risks, doctors strongly advise against taking ibuprofen in the third trimester.

Are There Any Safer Alternatives?

Yes! If you need pain relief during pregnancy, try these safer options: Acetaminophen (Tylenol) – The go-to pain reliever recommended by doctors for pregnancy.
Warm or cold compresses – Great for headaches, muscle pain, or backaches.
Prenatal massage or stretching – Can help with body aches and tension.
Hydration and rest – Sometimes, headaches and body pain improve with fluids and sleep. Always consult your doctor before taking any medication, even over-the-counter ones.

What If I Took Ibuprofen Before Knowing I Was Pregnant?

Don’t panic! If you took ibuprofen occasionally before realizing you were pregnant, the risk of harm is likely low. However, if you’ve been taking it regularly, let your doctor know so they can monitor your baby’s development.

When to Talk to Your Doctor

If you’re experiencing severe pain, fever, or inflammation, talk to your doctor about safe treatment options. They can guide you to medications or alternative remedies that won’t harm your baby.

The Bottom Line

Ibuprofen is not safe during pregnancy, especially in the third trimester, due to risks like heart problems, low amniotic fluid, and delayed labor. Instead, opt for acetaminophen (Tylenol) or other doctor-approved remedies for pain relief. Always check with your doctor before taking any medication while pregnant.

Content Reviewed by Dr V. profile picture

Content Reviewed by Dr V.

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Dr. Vaheh Shirvanian, a family medicine physician and father. With over 17 years of experience, he specializes in inpatient acute hospital care, outpatient family medicine, urgent care, emergency medicine, and hospice care. Dr. V is passionate about guiding new parents through the challenges and joys of parenthood, offering compassionate and expert support at every step.

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