Is It Safe to Take Cold Medications During Pregnancy? Here’s What You Need to Know
Catching a cold during pregnancy can be frustrating—especially when your usual go-to medications might not be safe for your baby. But don’t worry! While some over-the-counter (OTC) cold medications are safe, others should be avoided. Here’s a complete guide to help you navigate treating a cold while pregnant.
Are Cold Medications Safe During Pregnancy?
Some cold medications are considered safe during pregnancy, while others may pose risks. The key is to choose treatments that are pregnancy-friendly and avoid those that could harm your developing baby.The American College of Obstetricians and Gynecologists (ACOG) recommends using medications only when necessary and opting for the safest options available.
Safe Cold Medications During Pregnancy
If you need relief, here are some medications that are generally considered safe:Acetaminophen (Tylenol): Safe for fever, headaches, and body aches. Avoid ibuprofen (Advil) and aspirin.
Diphenhydramine (Benadryl) & Chlorpheniramine: Antihistamines that can help with runny nose and sneezing.
Saline Nasal Spray: A great drug-free way to relieve nasal congestion.
Menthol Rubs (Vicks VapoRub): Safe for congestion relief.
Honey & Lemon in Warm Water: Natural and effective for soothing a sore throat.
Cough Drops & Lozenges: Generally safe, but check for added ingredients like menthol or zinc.
Cold Medications to Avoid During Pregnancy
Ibuprofen (Advil, Motrin) & Aspirin: Can cause complications, especially in the third trimester.
Decongestants (Pseudoephedrine & Phenylephrine): Found in Sudafed and some cold medicines, these can affect blood flow to the placenta.
Certain Cough Syrups (Dextromethorphan with Alcohol): Always check the label for added alcohol or unnecessary ingredients.
Multi-Symptom Cold Medications: Many contain a mix of ingredients, some of which may not be safe. Stick to single-ingredient options instead.
Natural Ways to Relieve Cold Symptoms During Pregnancy
If you’d rather avoid medications, try these safe and effective home remedies:Stay Hydrated: Drink plenty of water, herbal teas, and warm broths.
Use a Humidifier: Adding moisture to the air can ease congestion and throat irritation.
Rest & Sleep: Your body needs extra rest to fight off infections.
Gargle with Salt Water: Helps soothe a sore throat.
Elevate Your Head While Sleeping: Reduces nasal congestion and improves breathing.
When to Call Your Doctor
Most colds go away on their own within a week, but call your doctor if you experience:A fever over 100.4°F (38°C)
Difficulty breathing or persistent chest pain
Severe sore throat with white patches (could indicate strep throat)
Symptoms lasting more than 10 days or worsening over time
Final Thoughts
Having a cold during pregnancy isn’t fun, but with the right approach, you can manage your symptoms safely. Always consult your doctor or pharmacist before taking any medication, and when in doubt, opt for natural remedies. Your health and your baby’s well-being are the top priorities!

Content Reviewed by Dr V.
Learn MoreDr. Vaheh Shirvanian, a family medicine physician and father. With over 17 years of experience, he specializes in inpatient acute hospital care, outpatient family medicine, urgent care, emergency medicine, and hospice care. Dr. V is passionate about guiding new parents through the challenges and joys of parenthood, offering compassionate and expert support at every step.